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Despite the only small benefits shown to Alzheimer's patients following clearance of amyloid-β aggregates in the aging brain, the consensus remains that a slow accumulation of amyloid-β aggregates over years is the inciting form of dysfunction that gives rise to the later tau aggregation …
The gut microbiome is made up of thousands of distinct microbial species, interacting with one another to process food and generate a broad range of metabolite molecules that are varying degrees of necessary, helpful, and harmful to the tissues of the body. The balance of these microbial…
Four major medical societies developed the framework, calling on providers to approach cardiovascular risk through a female-specific lens.
Biograph completed its first U.S. study integrating Caristo Diagnostics’ CaRi-Heart AI technology into its coronary CT angiography program. The study applied AI-enabled analysis alongside high-resolution CCTA and cardiometabolic profiling to evaluate coronary perivascular inflammation in…
One of the oldest and biggest longevity conferences moved this year across the Atlantic, from Copenhagen to Boston. The new location brought ARDD close to several important longevity hubs and might have contributed to this edition’s practical, entrepreneurial, and forward-oriented spirit. We have…
Rapalogix reports firmer, more elastic skin in a double-blind study of its longevity serum, and the details are worth a close read. Forty-seven women spent 12 weeks applying a serum to their faces twice a day. Thirty-one of them got the real formulation. The other 16 got a matching base without the…
Cognito Therapeutics and the state’s Life Science Hub are building a statewide platform around its Alzheimer’s therapy, Spectris. Cognito Therapeutics expects to report results from its pivotal HOPE trial later this year. Rhode Island is already making room for the company. On 13 October, the Rhode…
Swiss fertility heavyweight bets on stem-cell-derived egg maturation – and on ovarian biology as a market worth owning. Fifty-odd years into the business of helping people build families, Ferring would now like to own some of the cells as well. The Swiss pharmaceutical group has signed an agreement…
Life Biosciences (“Life Bio”), a biotechnology company pioneering cellular rejuvenation medicines to reverse diseases of aging, announced interim data from its Phase 1 clinical trial of ER-100 in three participants with open angle glaucoma (OAG). The data demonstrated that a single intravitreal…
In our systematic review and meta-analysis, we aimed to assess the predictive accuracy and clinical applicability of ten dementia risk assessment scores for incident dementia in cohort studies. Three of 10 risk scores had sufficient, comparable data for a meta-analysis. We analyzed the…
Longeveron released updated results from ELPIS II, its Phase 2b randomized trial of Laromestrocel given as an adjunct during Stage II palliative surgery in 40 infants with hypoplastic left heart syndrome. The trial did not meet its primary efficacy endpoint of change in right ventricular ejection…
Senescent cells accumulate with age to drive the onset and progression of age-related disease and loss of function. Over the past decade, a broad range of research and development efforts have emerged to attempt to address this cause of aging. Senostatic therapies reduce the pace at which senescent…
Researchers here relate an interesting story: they designed and synthesized a small peptide that is intended to interfere with an interaction between amyloid-β and zinc ions , with the aim of suppressing a necessary part of the process of amyloid-β aggregation . This amyloid-β aggregation…
Vadim Gladyshev, PhD, Professor of Medicine at Brigham and Women's Hospital, Harvard Medical School, elected to the National Academy of Science, is a prolific science of aging researcher. We covered many topics including: Subscribe now — The nature of aging, and how it is different from biological…
Few explicit policies exist to address cognitive decline among aging physicians, a study published in JAMA Health Forum found.
Nature Aging, Published online: 27 October 2026; doi:10.1038/s43587-026-01257-1 Yang et al. demonstrate that statins can compensate for reduced estrogen signaling in skeletal stem and progenitor cells, promoting bone anabolism during estrogen deficiency and suggesting therapeutic benefits beyond…
Microglia are innate immune cells of the brain, similar in behavior to tissue resident macrophages elsewhere in the body, but with an additional portfolio of duties relating to maintenance of neural networks . Like macrophages, microglia can adopt packages of behavior, and switch between them…
Researchers are developing biomedical repair therapies to address multiple age-related diseases at once, yet they are forced to put them through regulatory pathways built for single-disease drugs. The result is delay, duplication, and unnecessary cost precisely when speed matters the most. The…
Inside XPRIZE Healthspan’s $101m race: how teams are judged, why measurement matters, and what the field gains beyond a single winner. When a prize carries a $101 million price tag, you expect the conversation to be about the winner. On the latest episode of Longevity.Technology UNLOCKED , the…
As the FDA begins lifting hormone therapy warnings, Longevitix argues the next gap is a clinical system designed around the whole woman. For more than two decades, menopausal hormone therapy carried the most prominent safety warning the FDA can print. In February, the agency began taking parts of…
Beacon Biosignals acquired Snap Diagnostics, a home sleep testing provider operating in all 50 states. The acquisition more than doubles Beacon’s patient reach and establishes a national channel to bring EEG-enabled home sleep testing to primary care, telehealth, psychiatry and other specialty…
Prenuvo released research analyzing whole-body MRI and sleep data from 14,031 adults in collaboration with sleep scientists at UT Dallas. According to the company, the analysis found that higher sleep efficiency was associated with lower visceral fat and greater parietal gray matter volume, while…
Recovery and transplantation of organs following vitrification using cryoprotectant is an important step along the road to the future technological capability of whole body vitrification and recovery - and recovery of those individuals already preserved at low temperature by the cryonics industry …
I just received an order from Maulik, 400 rapacan tablets, which I ordered on October 5. I feel like that was very quick. He was great to work with. Question: how many tablets can a person reasonably order at a time? I’m planning to do another order to stock up a bit. Appreciate any advice.
Publication date: February 2027 Source: Neurobiology of Aging, Volume 170 Author(s): Jessica MacLean, Gavin M. Bidelman
Publication date: February 2027 Source: Neurobiology of Aging, Volume 170 Author(s): Yiran Du
Publication date: February 2027 Source: Neurobiology of Aging, Volume 170 Author(s): Hanie Karimi, Trevor Exell, Scott Peltier, Douglas Noll, Benjamin M. Hampstead, Alexandru D. Iordan, Jessica Damoiseaux, Ana M. Daugherty, Shruti Mishra
Publication date: February 2027 Source: Neurobiology of Aging, Volume 170 Author(s): Pietari Nurmi, Heidi Ala-Salomäki, Hanna Renvall, Mia Liljeström
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s):
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Tyler D. Robinson, Emily J. Van Etten, Shira Hao, William P. Milberg, Catherine B. Fortier, David H. Salat
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Yue Hong, Christa Michel, Gabriele Maria Gassner, Yiwen Zhang, Courtney Accorsi, Beau M. Ances, Lauren M. Antonucci, Steven E. Arnold, Ganesh M. Babulal, Susan Y. Bookheimer, Randy L. Buckner, Carlos Cruchaga…
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Shino Magaki, Spencer Tung, D. Jason Sinclair, Christopher K. Williams, Annlia Paganini-Hill, Adrian Murillo, Su Aung, Jeffrey Goldstein, Diana Vulcain, Noriko Salamon, Ariadna Martinez, Leopoldo Valiente Banuet…
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Siona Mishra, Corinne Pettigrew, Chidi Ugonna, Nan-kuei Chen, Jennifer B. Frye, Kristian P. Doyle, Lee Ryan, Marilyn Albert, Sara Grace Ho, Abhay Moghekar, Anja Soldan, Elizabeth R. Paitel
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Lihua Xia, Didac Vidal-Pineiro, Karin L. Meeker, Richard Henson
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Broderick M.B. Parks, Casandra Hayar, Debbie M. Kelly, Leslie S. Phillmore
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Shannon M. Drouin, Olivier Potvin, Harrison Fah, Kaarin J. Anstey, Mario Masellis, Simon Duchesne, Roger A. Dixon, for the Alzheimer’s Disease Neuroimaging Initiative
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Joseph A. McQuail, Carol A. Barnes, Jennifer L. Bizon, Sara N. Burke, John F. Disterhoft, Thomas C. Foster, Matt Huentelman, Catherine C. Kaczorowski, Jeffrey M. Long, Shannon J. Moore, Peter R. Rapp, Yaakov Stern…
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Georgia L. Nolt, Steven M. MacLean, Lesley R. Golden, Shealee P. Thorpe, Isaiah O. Stephens, Jessica L. Funnell, Chesney R. Brock, Chloe C. Lucido, Lily Smith, Gabriela Hernandez, Jose M. Arbones-Mainar, Cecily…
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Jia-Jie Xu, Erin Goddard, Roger A. Dixon, Ranmalee Eramudugolla, Runyu Huang, Hai-Xin Jiang, Kaarin J. Anstey
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s):
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Siarhei A. Dabravolski, Daria D. Borodko, Stanislav A. Antonov, Svetlana S. Lukina, Andrey A. Poletaev, Vasily N. Sukhorukov
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Sofia-Panagiota Giannakopoulou, Christina Chrysohoou, Smaragdi Antonopoulou, Fotios Barkas, Nikos Vlachogiannis, Evrydiki Kravvariti, Evangelos Liberopoulos, Christos Pitsavos, Costas Tsioufis…
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Deborah Beckerová, Martin Pesl, Hana Dobrovolná, Vladimir Rotrekl
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Neda Hedari, Andrew Hesketh, Susan Sandeman, Nathan A. Davies, Naomi Baker, Richard G.A. Faragher
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Giulia Matacchione, Sara Caccese, Chiara Giordani, Matilde Sbriscia, Sonia Fantone, Angelica Giuliani, Jacopo Sabbatinelli, Niki Tombolesi, Francesca Marchegiani, Rina Recchioni, Valeria Morichi…
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Sergey V. Ivanov, Victor Paromov, Metin L Aksu, Harshana Rajakaruna, Jane Tonello, Salvador González-Ochoa, Muna Mohammed, Tonie Farris, George Babineaux, Sanika S. Chirwa, Anil Shanker, Alla V…
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Darab Ghadimi, Sophia Blömer, Aysel ŞAHİN KAYA, Sandra Krüger, Christoph Röcken, Heiner Schäfer, Geraldine de Heer, Dominik Jarczak, Jumpei Uchiyama, Shigenobu Matsuzaki, Wilhelm Bockelmann
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Manh Dat Duong, Soo-A. Kim, Sang-Gun Ahn
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Xinyi Li, Zhifang Fu, Dan Sun, Zirun Jin, Hongmei Jiao
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Dan Keren, Roee Hayek, Yoel Toledano, Tzipi Strauss, Shmuel Springer, Abigail Goshen
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Karima Djabali
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Sergio Linsambarth, Alejandra Lopez-Moroni, Cesar Casanova, Simon Alarcon, Loreto Araos, Andrea Puebla-Huerta, Fabian Jaña, Alenka Lovy, Carlos Villalobos, J. Cesar Cárdenas
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Matthew W. Simonson, Weilan Wang, Jian Hua Tay, Sharon Hameed, Chong Hui Min, Atikah Khan, Arun Reji, Andrea B. Maier
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Vladimir A. Martínez-Rojas, Diana A. Rosas-García, Gabriela Rocha-Botello, Luis A. Márquez, Gabriel Herrera-Lopez, Isabel Sollozo-Dupont, Perla Moreno-Castilla, Emilio J. Galván
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Abdel Halim Harrath, Maroua Jalouli, Md Ataur Rahman, Valter Longo
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Zeyu Cui, Yanchen Lai, Xiangfeng Chen, Chunxia Wang, Bimeng Zhang, Te Liu
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Liana Cerioni, Mattia Tiboni, Noemi Pappagallo, Serena Benedetti, Maria Cristina Albertini, Roberto Verucchi, Lucrezia Aversa, Andrea Gorassini, Annalisa Aluigi, Luca Casettari, Enrique Llobet-Serra…
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Surya Prakash Bhatt, Shivam Pandey, Anoop Misra
Publication date: Available online 23 October 2026 Source: Mechanisms of Ageing and Development Author(s): Maria Charalampopoulou, George C. Zografos, Dimitrios Tsakogiannis, Ioanna A. Anastasiou, Garyfalia Bletsa, Dimitrios Tryfonopoulos, Panagiotis Daskalakis, George P. Chrousos, Flora…
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Clodagh Bottomley, Evelyne Liuu, Beatriz Echarte Archanco, Danielle Harari, Tania Kalsi, Carlos de Pablo Gallega, Carly Welch
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Silvia Sideri, Marianna Cosentino, Laura Forcina, Antonio Musarò
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Giulia Bonvini, Davide Sattin, Nunzio Iraci, Gabriella Dobrowolny, Maria Cristina De Cola, Antonio Musarò, Christian Lunetta, Aida Zulueta
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Saba Khatatneh, Csaba Sőti, Milán Somogyvári
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Giusy Bergamo, Mariana Fernandes, Silvia Maio, Gianluca Albanesi, Matteo Antonucci, Ilaria Barbaro, Flavia Cirillo, Luca Fernando, Giulia Amicucci, Diego Centonze, Claudio Liguori
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Meng Hao, Shuishan Zhang, Xueqing Li, Hui Zhang, Yi Li, Xiaofeng Wang, Andrew D. Rutenberg, Alan A. Cohen
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Yugan Gogul Muthukumar, Karthikeyan A. Vijayakumar, Gwang-Won Cho
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Lingjie Meng, Yang Liu, Xiaocong Li, Xin Xiao, Xinyi Du, Fang Liu, Yi Xiao
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Alkinoos A. Armoundas, Christina Piperi
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Kangrui Liu, Yiming Cao, Yizhou Gu, Yue Wang, Lei Jin, Airan Liu, Jingxue Wang, Song Chen
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Julij Šelb, Leon Deutsch, Matej Červek, Metta Bernou Pratt, Leon Bedrač, Domen Mohorčič, Natalija Sebanc, Urška Ašič, Sanja Terzič, Enej Kuščer, Andrea Britta Maier, Filip Cvetko
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Denisa FV Pirscoveanu, Mihai-Cristian Papa, Britta Kaltwasser, Dirk M. Hermann, Ulf Brockmeier, Andrea Cercel, Anthony Oliver, Johannes Grillari, Marius Viorel Ionica, Aurel Popa-Wagner
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Carmela Rita Balistreri, Alessia Di Salvo, Chiara Motisi, Miriam Carella, Francesco Gervasi, Carlotta Camilli, Tommaso Silvano Aronica
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Tsz Yan Wong, Alexandra C. Gillett, Rodrigo R.R. Duarte, Leena Habiballa, Helen L. Fisher, Veryan Codd, Timothy R. Powell
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Taihao Quan
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Brittany Intzandt, Zacharie Potvin-Jutras, Claudine J. Gauthier
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s):
Publication date: Available online 12 September 2026 Source: Mechanisms of Ageing and Development Author(s): V. Calabrese, G. Scapagnini, A. Ravagna, C. Colombrita, F. Spadaro, D.A. Butterfield, A.M. Giuffrida Stella
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Kenneth R. Paap, John Majoubi, Joo Hee Won
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Sadia Hasan, Rolan Al Shareef, Bushra Shaida, Zunaira Siddiqui
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Maulilio John Kipanyula
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