Mind & Brain · Europe
Was Maximierer und Genügsame unterscheidet – und wer am Ende zufriedener ist
Wer immer die beste Wahl treffen will, macht sich das Leben unnötig schwer, weiß der Neuroforscher Henning Beck. Er erklärt, mit welchen Tricks sich bessere Entscheidungen treffen lassen – und warum Perfektionisten oft unzufriedener sind.
Trump reopened an LGBTQ+ suicide hotline. But the department that runs it vows to ‘restore biological truth’
While organizations celebrate the reinstatement of the ‘press 3’ option by Samsha, details about rollout and training counselors remain secret For nearly three years, counselors through the 988 Suicide & Crisis Lifeline for LGBTQ+ individuals answered more than 1.5m calls, texts and online chats –…
Spätdiagnose AuDHS als Frau: Schritt für Schritt ins Leben
22 Jahre, einen Klinikaufenthalt und zwei Diagnosen brauchte es für meinen Start in den Heilungsprozess. Heute lebe ich glücklich – als Autistin mit ADHS
Warum verordnen und verkaufen wir Medikamente nicht stückgenau?
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Therapeut: „Werden Kinder ständig mit Medien beruhigt, können ihnen wichtige Lernerfahrungen fehlen“
Wer schon früh lernt, Gefühle mit dem Bildschirm zu verdrängen, kann später Schwierigkeiten haben, den Medienkonsum zu regulieren, warnt ein Therapeut – und gibt Tipps, wie Eltern ihre Kinder beim Umgang mit sozialen Medien unterstützen können
I was on Instagram so much, I was missing out on my young children’s lives | Letters
Emma Roberts on experiencing life in the real world rather than on social media. Plus letters from Warwick Mihaly , Madison Heckel , Zainab Chasb , Helen Clutton and Gordon Smart Like Georgina McNamara ( The one change that worked: I deleted Instagram – and embraced the joys of a truly private…
Plastische Chirurgin: "Für jede Frau gibt es die ideale Operationsmethode bei Brustkrebs"
Eine Brustkrebsdiagnose ist erst einmal ein Schock. Dann folgt oft die Frage: wie wird meine Brust danach aussehen? Expertin Elisabeth Russe klärt auf
Neurophysiological signatures underlying preserved lexical-semantic proficiency in healthy aging
Publication date: February 2027 Source: Neurobiology of Aging, Volume 170 Author(s): Pietari Nurmi, Heidi Ala-Salomäki, Hanna Renvall, Mia Liljeström
The effect of neurodegeneration on ultrasonic vocalisations (USV) and their neuronal substrates in mice and rats: A systematic review
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Charissa Calemi, Rose Bruffaerts, Tommas Ellender
Association of mitochondrial copy number and heteroplasmy with cognitive function in the ACCORD trial
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Michelle C. Odden, Yongmei Li, Vasantha Jotwani, Meghana S. Eswarappa, Rebecca Scherzer, Michael G. Shlipak, Dan E. Arking, Wen Shi, Joachim H. Ix, Robyn Jones, Anima Sharma, Lea McGeever, Pierre-Yves Desprez…
Regional distribution of mineralized blood vessels in Alzheimer disease and clinicopathological associations: A multicenter autopsy study
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): David Garcia, Naomi Saito, Shyam Tamizharasu, Louise Nicole C. Sevilla, Melanie N. Luu, Laurel Beckett, Lawrence S. Honig, Charles S. DeCarli, David G. Coughlin, Andrew F. Teich, Dan M. Mungas, Lee-Way Jin, Lorena…
Structural brain indicators of cognitive performance in middle and late adulthood: The Human Connectome Project in Aging/Aging Adult Brain Connectome cohort
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Yue Hong, Christa Michel, Gabriele Maria Gassner, Yiwen Zhang, Courtney Accorsi, Beau M. Ances, Lauren M. Antonucci, Steven E. Arnold, Ganesh M. Babulal, Susan Y. Bookheimer, Randy L. Buckner, Carlos Cruchaga…
Neuropathology of centenarians and supercentenarians: An autopsy study
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Shino Magaki, Spencer Tung, D. Jason Sinclair, Christopher K. Williams, Annlia Paganini-Hill, Adrian Murillo, Su Aung, Jeffrey Goldstein, Diana Vulcain, Noriko Salamon, Ariadna Martinez, Leopoldo Valiente Banuet…
Plasma inflammatory markers and brain white matter microstructure in late middle-aged and older adults
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Siona Mishra, Corinne Pettigrew, Chidi Ugonna, Nan-kuei Chen, Jennifer B. Frye, Kristian P. Doyle, Lee Ryan, Marilyn Albert, Sara Grace Ho, Abhay Moghekar, Anja Soldan, Elizabeth R. Paitel
Bilingualism modulates baseline brain–cognition relationships in aging: Evidence from the HABS-HD cohort
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Lihua Xia, Didac Vidal-Pineiro, Karin L. Meeker, Richard Henson
Spatial brain structures are selectively preserved during aging in homing pigeons ( Columba livia ), an avian spatial specialist
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Broderick M.B. Parks, Casandra Hayar, Debbie M. Kelly, Leslie S. Phillmore
Individual Differences in Cognitive Aging Rodent Datasets (ID-CARD): A collaborative platform for behavioral analysis across the lifespan
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Joseph A. McQuail, Carol A. Barnes, Jennifer L. Bizon, Sara N. Burke, John F. Disterhoft, Thomas C. Foster, Matt Huentelman, Catherine C. Kaczorowski, Jeffrey M. Long, Shannon J. Moore, Peter R. Rapp, Yaakov Stern…
Sex difference in brain reserve of working memory among older adults
Publication date: January 2027 Source: Neurobiology of Aging, Volume 169 Author(s): Jia-Jie Xu, Erin Goddard, Roger A. Dixon, Ranmalee Eramudugolla, Runyu Huang, Hai-Xin Jiang, Kaarin J. Anstey
Stratifying Heterogeneity in Mild Cognitive Impairment: A Multimodal Subtype and Stage Inference Approach
Publication date: Available online 24 October 2026 Source: Neurobiology of Aging Author(s): Chiari-Correia Rodolfo, Soares-Rodrigues Vinícius, Biondo Francesca, Young Alexandra, Oxtoby Neil, Cole James, Salmon-Garrido Carlos, for the Alzheimer’s Disease Neuroimaging Initiative
Aging-associated loss of CPEB4 impairs mitochondrial adaptation and promotes stress-induced senescence in alveolar type II cells
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Xinyi Li, Zhifang Fu, Dan Sun, Zirun Jin, Hongmei Jiao
Endogenous androgens, physical and cognitive function in healthy midlife men: A systematic review
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Dan Keren, Roee Hayek, Yoel Toledano, Tzipi Strauss, Shmuel Springer, Abigail Goshen
Loss of Ca 2 + signaling fidelity during aging: Mitochondrial dysfunction, senescence, and cognitive–motor decline
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Sergio Linsambarth, Alejandra Lopez-Moroni, Cesar Casanova, Simon Alarcon, Loreto Araos, Andrea Puebla-Huerta, Fabian Jaña, Alenka Lovy, Carlos Villalobos, J. Cesar Cárdenas
Metformin therapy increases leukocyte telomere length, telomerase activity, and longevity gene expression in Asian Indians with prediabetes: A 24-week participant-blind, outcome-assessor–blinded randomized controlled trial
Publication date: December 2026 Source: Mechanisms of Ageing and Development, Volume 234 Author(s): Surya Prakash Bhatt, Shivam Pandey, Anoop Misra
To longevity and beyond: A systems view of aging and stress resilience
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Silvia Sideri, Marianna Cosentino, Laura Forcina, Antonio Musarò
Beyond neurodegeneration: Systemic confounders of blood neurofilament light chain in aging and their implications for neurological biomarker interpretation
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Giulia Bonvini, Davide Sattin, Nunzio Iraci, Gabriella Dobrowolny, Maria Cristina De Cola, Antonio Musarò, Christian Lunetta, Aida Zulueta
Puerarin extends lifespan and enhances the resistance to oxidative stress through AMPK/TFEB mediated autophagy in Caenorhabditis elegans
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Lingjie Meng, Yang Liu, Xiaocong Li, Xin Xiao, Xinyi Du, Fang Liu, Yi Xiao
Epigenetic drift and LINE-1 activation in aging brain: Implications for neurodegenerative disease
Publication date: October 2026 Source: Mechanisms of Ageing and Development, Volume 233 Author(s): Alkinoos A. Armoundas, Christina Piperi
Expression of Concern to “Increased expression of heat shock proteins in rat brain during aging relationship with mitochondrial function and glutathione redox state” [Mech. Ageing Dev. 125(2004) 325-35]
Publication date: Available online 12 September 2026 Source: Mechanisms of Ageing and Development Author(s): V. Calabrese, G. Scapagnini, A. Ravagna, C. Colombrita, F. Spadaro, D.A. Butterfield, A.M. Giuffrida Stella
Cognitive reserve reconsidered: Asymmetry across proxies challenges a domain-general mechanism
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Kenneth R. Paap, John Majoubi, Joo Hee Won
Neurodegeneration in sub-Saharan Africa: Intersections of biological ageing, genomic diversity and the lifetime exposome
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Maulilio John Kipanyula
Heart–brain co-ageing: Phenotypic heterogeneity, molecular mechanisms and translational interventions
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Haozhang Huang, Weipeng Zhang, Cailan Hou, Xiaozhao Lu, Huangtao Ruan, Jin Liu, Tong Lei, Shiqun Chen, Ming Chen, Yong Liu
Turning back the ageing clock? Brain age in neuroprotective and clinical interventions
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Yuke Luo, James H. Cole, Hanna Lu
Lifelong Epstein-Barr virus persistence as a stress test of ageing immune surveillance: From infectious mononucleosis to chronic active EBV disease and virus-associated malignancy
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Yue Cao, Yanying Liang, Chenxi Zhao, Zhe Zhou, Shenglei Yu, Qingluan Yang, Lingyun Shao
What can narcolepsy teach us about hypocretin and dementia?
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Renata K. Carvalho, Tathiana A. Alvarenga, Fernando M.S. Coelho, Sergio Tufik, Monica L. Andersen
Redox–mitochondrial crosstalk in neurotoxicity: Regulated cell death pathways and neuroprotective strategies
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Kunal Bhattacharya, Nongmaithem Randhoni Chanu, Pukar Khanal, Dibyajyoti Das
Nuclear medicine-based diagnosis and therapeutic strategies for neurodegenerative diseases: Clinical progress
Publication date: January 2027 Source: Ageing Research Reviews, Volume 123 Author(s): Yi Li, Ke Pu, Deqiang Li, Yijin Zhao, Qixin Cai, Xin Zhou, Shaoqing Li, Yue Chen, Zhijun Zhou, Yang Liu
Decoding SUMOylation as a metabolic stress sensor in aging and age-related disorders: Mechanisms, tissue specificity and therapeutic potential
Publication date: November 2026 Source: Ageing Research Reviews, Volume 122 Author(s): Xinyue Liu, Shuanghong Chen, Dongcan Liu, Siyu Zou, Liming Deng, Ye Gao, Wanqian Xu, Yining Xie, Jie Peng, Liang Hao
Convergent vulnerability and divergent outcomes of the dopaminergic system in Parkinson’s and Alzheimer’s diseases
Publication date: November 2026 Source: Ageing Research Reviews, Volume 122 Author(s): Yu-ting Xi, Chen-xi Jia, Hui-dan Wang, Pei-yao Liu, Peng Li, Qianqian Niu, Ya-ling Yin
Experience-dependent plasticity of large-scale brain networks in aging: How different training modalities shape neural connectivity
Publication date: November 2026 Source: Ageing Research Reviews, Volume 122 Author(s): Federico Gennaro, Lorenzo Pini, Maurizio Corbetta, Eling D. de Bruin, Patrick Manser, Tatiana Moro, Marika Berchicci, Antonio Paoli
Targeting senescence-associated biomarkers: Emerging strategies for anti-ageing therapy
Publication date: November 2026 Source: Ageing Research Reviews, Volume 122 Author(s): Zhe Qin, Lu Zhang, Jianping Song, Yifan Chen, Yidan Zhou, Jizhun Wu, Xiang Li, Liang Chen, Zhuolong Zhou
Vaccination strategies in neurodegenerative proteinopathies
Publication date: November 2026 Source: Ageing Research Reviews, Volume 122 Author(s): Chunhao Tao, Deming Zhao, Lifeng Yang
Neuro-metabolic ageing drives diabetes-associated neurodegeneration: A geroscience and network pharmacology perspective
Publication date: November 2026 Source: Ageing Research Reviews, Volume 122 Author(s): Sakshi Tiwari, Bilal Siddiqui, Saman Fatima, Monica Saifi, Imran A. Khan, M.Z. Abdin
A los españoles no les da miedo envejecer, pero les aterra el deterioro cognitivo
El 69% de los encuestados en el Stada Health Report afirman que lo que más les asusta de hacerse mayores es el deterioro cognitivo. El mismo informe recoge que los ciudadanos quieren dar espacio a la IA en su salud, pero sin sustituir nunca al médico.
Des supraconducteurs aux bulles de savon, la matière condensée fait le point à Toulouse
Pendant une semaine, du 26 au 30 octobre, 800 scientifiques présentent leurs travaux de recherche lors d’une grande conférence à l’université Paul-Sabatier, à Toulouse. Un instantané de la recherche française dans un domaine qui s’étend des matériaux de l’électronique aux mousses et aux tissus…
Cinéma, art, science… pourquoi le cachalot est partout
Du grand écran aux musées, des livres aux laboratoires, le cachalot multiplie les apparitions. Une étonnante omniprésence qui témoigne aussi du regard nouveau que nous portons sur ce géant des mers.
Des organoïdes cérébraux cultivés pendant cinq ans reproduisent le développement du cerveau humain
Des chercheurs ont maintenu actifs pendant cinq ans des modèles qui reproduisent certaines structures du cerveau humains. Leur maturation reproduit plusieurs étapes du développement du cerveau, du stade fœtal aux premières années après la naissance.
Haines tribute speeches to open parliament, but Labor mustn’t overlook broader causes of boiling anger | Josh Butler
Poverty, health and dislocation are fuelling political anger. Labor can’t ignore this in response to alleged attack on Indi MP Follow our Australian politics live blog for latest updates Get our daily political email , free app or daily news podcast Federal parliament will commence on Monday…
„Wenn die Eltern alles selbst erzählen, hilft das weder der Sprachentwicklung noch dem Gehirn“
Geschichten haben eine erstaunliche Wirkung auf die emotionale und kognitive Entwicklung von Kindern. Elain Reese erforscht seit Jahrzehnten, wie Eltern narrative Fähigkeiten fördern können – und dabei selbst keine begabten Erzähler sein müssen.
„Einzelne Regelbrecher nehmen der Gruppe die Leitplanken“
Schummeln, Straßenverkehrsregeln ignorieren, Vordrängeln: Ein Experiment zeigt, wie aus kleinen Regelverstößen eine Eskalation werden kann. Wer ist dafür empfänglich?
Brain-zapping patch to help sleep could also ease anxiety
A skin patch on the face at night could increase the time spent in deep sleep - which is vital for protecting the brain against stress, depression and possibly even dementia
Drugs that cool brain can save patients before they reach A&E
People who have a cardiac arrest could also benefit from a form of the treatment with everyday tablets - paracetamol, aspirin or ibuprofen
Leben bis 150? Nein danke. Aber gesund alt werden gerne. So kann es gelingen
Viele "Anti-Aging-Wunder" sind wissenschaftlich nicht ausreichend belegt. Die Geriaterin Anna Chodos plädiert für einen anderen Ansatz: Entscheidend ist, wie lange man gesund, selbstständig und aktiv bleibt
Astéroïde Bennu : ce que les échantillons révèlent sur les origines du Système solaire
La sonde spatiale Osiris-Rex, de la Nasa, a rapporté sur Terre des échantillons de l’astéroïde Bennu. Leur analyse apporte de précieuses informations sur la formation du Système solaire, sur la chimie prébiotique et même sur nos stratégies de défense planétaire.
The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cells
In young animals, oligodendrocyte progenitor cells (OPCs) in the CNS efficiently differentiate into myelinating oligodendrocytes (OLs), whereas ageing reduces this capacity, impairing remyelination following demyelinating injury and adaptive myelination involved in learning. To identify factors…
Zellbiologe: "Das Immunsystem braucht keinen Booster"
Schutz vor Infekten aus der Pillendose? Nein, sagt Zellbiologe Stephan Barth, das Immunsystem lässt sich nicht auf Knopfdruck hochfahren. Der wirklich potente Wirkstoff ist der eigene Lebensstil
Under-25s with ADHD and anxiety could get discount gym memberships
Young people suffering from mental health problems and conditions like ADHD could be prescribed gym memberships, gardening clubs and other social activities instead of medication alone as part of government welfare and health reforms. Professor Peter Fonagy, who led a major government review into…
We are reclaiming real life after getting rid of Instagram | Letters
Readers on taking back their lives – and brains – from social media algorithms I couldn’t agree more with Georgina McNamara ( The one change that worked: I deleted Instagram – and embraced the joys of a truly private life, 19 October ). Reading about the sheer relief of stepping away from Instagram…
Du Big Bang à aujourd’hui : l’histoire de l’Univers en sept grandes étapes
Inflation, premières particules, naissance des étoiles, matière noire, expansion accélérée… Le physiciens théoricien Yann Mambrini retrace les grandes phases de l’histoire de l’Univers et explore les scénarios possibles pour son avenir dans son nouveau livre « Il était sept fois l’Univers » (Albin…
I thought I was dying but it was health anxiety - here's how to recognise the signs
Hollie Sharman shares her experience of health anxiety and a doctor advises on how to manage symptoms.
Wat te doen als je baby niet slaapt?
Jonge ouders krijgen te maken met weinig slaap en veel ongevraagde adviezen. Ontwikkelingspsycholoog Roseriet Beijers weet hoe pittig het kan zijn, en steekt hen graag een hart onder de riem.
Muss ich meine Eizellen einfrieren lassen? Zukunftssorgen einer 21-Jährigen
Sorgen schwirren mir viele durch den Kopf – Unfruchtbarkeit war bisher noch keine davon. Dabei sinkt die Fertilität der Frau ab Mitte 20, lerne ich bei einem Lunch rund um Kinderwunschbehandlungen
‘We can’t just pretend that everything’s OK in the regions’: what went wrong in Wangaratta?
After Indi MP Helen Haines was allegedly attacked on Monday, people across the electorate are questioning how something like this could happen – and if anything could have been done to prevent it Something changed a few years ago. Brendan Nugent had been a reasonably prominent conservationist when…
NHS supports record numbers of people living with dementia as target achieved
Dr Jeremy Isaacs, National Clinical Director for Dementia, NHS England, said: “It is fantastic news that the NHS has hit its target for diagnosing more than two thirds of people with dementia for the first time since before the COVID-19 pandemic – and 50,000 more people than the last time this…
Gibt es hier Erfahrungen mit einer Dysautonomie des Nervensystems?
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Walking 8,875 steps per day could boost your brain health, a study suggests
People who walked more consistently performed better on tests measuring attention, focus and decision-making, measures of cognitive health, a new study suggests.
Diabetes and ADHD drugs to be tested on Alzheimer's patients in new study
Drugs will be tested simultaneously, which it's hoped will speed up the process of finding new treatments for this common type of dementia.
Rentiert sich eine Sonderklasse Versicherung ohne Selbstbehalt?
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Burnham backs mandatory suicide prevention training for social workers after parent-carer Matilda Davis’s death
Former art teacher, who cared for her disabled son, ‘received almost no support’, said her local MP Manuela Perteghella Andy Burnham has backed mandatory suicide prevention training for social workers after the “devastating” death of Matilda Davis, a parent-carer who killed herself minutes after…
[La semaine en bref] Quelques grammes de Phobos
Le Japon lance une mission spatiale ambitieuse pour ramener, d’ici à cinq ans, une dizaine de grammes de Phobos, l’une des deux lunes de Mars. Un positron, l’antiparticule de l’électron, s’est retrouvé piégé plusieurs mois, et devrait livrer des premiers secrets sur l’antimatière. Et aussi, perdre…
L’intelligence artificielle peut-elle remplacer les mathématiciens ? L’analyse de Terence Tao
Les résultats spectaculaires obtenus en mathématiques par des modèles d’IA ces derniers mois ont bouleversé la communauté des mathématiciens. Terence Tao, l’un des plus grands mathématiciens contemporains, analyse les impacts profonds de ces nouveaux outils, entre étonnement, enthousiasme et…
First a strip-search goes too far, then a boy is isolated in a cell … the former detainees who tell all-too-similar stories
Exclusive: Guardian Australia has spent five months talking to men and women who are speaking out at last, alleging systemic assaults in custody across the country Warning: This article contains allegations of child sexual abuse some readers might find distressing Find more from the Duty of Care…
Mark Allen reveals he made snooker return after 10-week stay in mental health clinic
Former world No 1 vows to show ‘fighting qualities’ ‘I see the light now that I couldn’t see before’ Mark Allen has revealed he spent 10 weeks in a mental health clinic before discharging himself to play in this week’s Northern Ireland Open . In a long statement posted on X, the 40-year-old said he…
Gaslighting: Wie man psychischen Missbrauch erkennt – und wie man sich löst
Wer ständig hört, dass er übertreibt oder sich Dinge einbildet, beginnt an sich zu zweifeln. Gaslighting untergräbt das Vertrauen in die eigene Wahrnehmung. Besonders tückisch ist, wie unauffällig es oft beginnt
MenoDay: Was Frauen in den Wechseljahren brauchen
Erleben wir gerade einen Wandel im Umgang mit der Menopause oder vor allem einen neuen Hype
Record numbers of Britons diagnosed with dementia, NHS figures show
This is the first time in six years that the NHS has met its target to ensure two thirds of over-65-year-olds suffering symptoms of the condition have a formal diagnosis.
Comment faire monter de l’eau sans pompe grâce au « bélier hydraulique »
La surpression qui apparaît lorsqu’on ferme brusquement un robinet peut endommager les canalisations, mais elle peut aussi être exploitée pour faire remonter de l’eau sans moteur.
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